在治疗原发性先天性玻璃眼瘤后的手术结果
Ayaka Edo1,2, Kazuyuki Hirooka3, Hideaki Okumichi3,4
1Department of Ophthalmology and Visual Science, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan. ayakae@hiroshima-u.ac.jp.
Japanese journal of ophthalmology
|January 24, 2025
概括
轨道切除术对初级先天性玻璃眼 (PCG) 有效,大多数病例通过三种手术得到控制. 较大的角膜直径增加了需要多次玻璃眼手术的风险.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼研究研究 玻璃眼研究
- 儿科眼科医生 儿科眼科医生
背景情况:
- 初级先天性玻璃眼 (PCG) 是一种罕见的,严重的玻璃眼形式,在出生时出现.
- 有效的手术管理对于保护PCG患者的视力至关重要.
- 轨道切除术是PCG的常见手术选择,但重新手术的结果和风险因素需要进一步调查.
研究的目的:
- 评估trabeculotomy作为日本患者PCG的初级手术程序的结果.
- 确定与需要PCG多发性玻璃眼外科手术相关的临床和人口风险因素.
主要方法:
- 这是一项回顾性观察性研究,包括2006年至2021年期间接受初始青光眼手术的日本PCG患者.
- 分析了手术结果,将患者分为单次和多次手术组.
- 采用多变量物流分析来确定需要多次手术的风险因素.
主要成果:
- 分析了20名PCG患者的20只眼睛,所有这些患者最初都接受了外侧带切除术.
- 在5年内,最多三次气管切除术的累计成功率为89.7%.
- 55%的眼睛只需要一次手术,45%需要两次或更多手术.
- 较大的角膜直径 (1毫米增加) 与多次手术风险增加16倍 (p=0.047) 有关.
- 单次手术组在最后一次访问时表现出明显更好的最佳校正视敏度和更小的圆柱形功率.
结论:
- 轨道切除术是PCG的成功手术干预,即使在最多三次手术后,成功率也很高.
- 角膜直径的扩大是PCG患者需要多重青光眼手术的重要预测因素.
- 这些发现可以帮助患者选择和PCG管理的手术规划.
相关概念视频
01:28Angle Closure Glaucoma: Treatment
433
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
433
01:25Glaucoma: Overview
497
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
497
01:27Open Angle Glaucoma: Treatment
389
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
389