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Updated: May 31, 2025

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction
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Published on: January 29, 2019

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药理动力学和暴露反应建模支持基于身体表面积的Farletuzumab Ecteribulin剂量在日本患有固体瘤的患者中

Seiichi Hayato1, Lora Hamuro2, Toshio Shimizu3,4

  • 1Eisai Co. Ltd., Tokyo, Japan.

Journal of clinical pharmacology
|January 24, 2025
PubMed
概括

法勒图祖马布 (Farletuzumab ecteribulin) 在卵巢和肺癌中显示出抗瘤活性. 与体重剂量相比,体表面积剂量可以通过降低间歇性肺病风险来提高安全性.

关键词:
抗体药物合物 抗体药物合物剂量优化剂量优化暴露反应分析.卵巢癌是发生在卵巢的癌症.人口的药理动力学

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