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Updated: May 31, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
10:33

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Published on: October 26, 2015

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循环素依赖性激酶抑制剂AT7519是一种人类RORγt激活剂

Kaja Karaś1, Joanna Pastwińska1, Anna Sałkowska1

  • 1Laboratory of Epigenetics, Institute of Medical Biology, Polish Academy of Sciences, Łódź, Poland.

Immunology and cell biology
|January 24, 2025
PubMed
概括

AT7519激活免疫细胞中的RORγt,增强抗癌反应. 这一发现表明,AT7519可以促进抗PD-1和抗CTLA4治疗等癌症免疫疗法.

关键词:
在AT751919的时间里,在IL17中,IL17是IL17.罗尔特的时间.肝细胞癌是肝细胞癌.

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