相关实验视频

Updated: May 31, 2025

Quantitative Analysis of Alternative Pre-mRNA Splicing in Mouse Brain Sections Using RNA In Situ Hybridization Assay
11:22

Quantitative Analysis of Alternative Pre-mRNA Splicing in Mouse Brain Sections Using RNA In Situ Hybridization Assay

Published on: August 26, 2018

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全转录组的替代mRNA拼接分析揭示了神经元分化的转录后调节

Yuan Zhou1, Sherif Rashad1,2, Kuniyasu Niizuma1,2,3

  • 1Department of Neurosurgical Engineering and Translational Neuroscience, Tohoku University Graduate School of Medicine, Sendai, Japan.

The FEBS journal
|January 24, 2025
PubMed
概括

像PTB和HuR这样的RNA结合蛋白 (RBPs) 的替代拼接 (AS) 调节对于神经元差异化至关重要. 它们的淘汰增强了分化,并在转录后改变了基因表达.

关键词:
在PTB,HuRR.在SH-SY5YY中.另一个替代拼接方法是拼接.神经退行症的神经退行症神经元分化神经元的分化

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