作为结核病控制计划的一部分,在山羊身上进行解剖病理学检查的价值,具有阳性比较性皮内结核素测试,作为结核病控制计划的一部分
Jose A Navarro1, Joaquin Sanchez1, Antonio J Buendia1
1Departamento de Anatomía y Anatomía Patológica Comparadas, Facultad de Veterinaria, Universidad de Murcia, Murcia, Spain.
The Veterinary record
|January 24, 2025
概括
尸检证实,山羊结核病 (TB) 检测中的错误阳性是由于结核病或Corynebacterium伪结核病感染,而不是结核病. 这凸显了死后分析在准确诊断山羊结核病方面的价值.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 传染性疾病 传染性疾病
- 动物卫生 动物健康
背景情况:
- 由Mycobacterium bovis和Mycobacterium caprae引起的结核病是使用比较性皮内结核素 (CIT) 试验来管理的.
- 由于感染Corynebacterium伪结核病或Mycobacterium avium亚种结核病 (MAP),CIT测试的特异性可能会受到损害.
- 较低的阳性预测值需要进行死后检查,以准确验证结核病状况.
研究的目的:
- 通过使用CIT测试,调查山羊结核病测试中虚假阳性结果的原因.
- 评估死后检查在确认山羊结核病状况方面的有用性.
主要方法:
- 在2015年至2020年期间,来自14个羊群的37只CIT阳性山羊接受了尸检.
- 在穆尔西亚兽医医学院进行了解剖病理学分析.
主要成果:
- 尸检排除了所有采样山羊的结核病变.
- 在23只山羊中发现了帕拉结核病 (MAP感染),在6只山羊中发现了Corynebacterium伪结核病感染.
- 在参加的群体中,直到2023年,没有观察到正反应器的复发.
结论:
- 解剖病理学检查是一种有效,快速和经济高效的方法,用于确定山羊群的结核病状况.
- 该研究确定了MAP和Corynebacterium伪结核病是山羊中虚假阳性CIT测试结果的常见原因.
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