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Updated: Jun 23, 2026

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单细胞转录基因分析揭示了骨和脂肪中的生物力学负荷诱导的不平衡,导致腰椎间盘骨化核脉性退化

Ping Zhang1, Yuan Wang1, Jianqi Bai1

  • 1Department of Pathology, Wangjing Hospital of China Academy of Chinese Medical Sciences, Beijing, China.

Journal of cellular physiology
|January 24, 2025
PubMed
概括

生物力学负荷通过改变骨脂肪平衡和促进骨质分化驱动腰椎椎间盘退化 (IVDD) 骨化. 这项研究确定了IVDD的新型细胞机制和潜在生物标志物.

关键词:
生物机械负荷 生物机械负荷骨脂平衡的原因是骨脂的平衡.椎间盘退化 椎间盘退化它的核是脉冲的脉冲.骨化 骨化 骨化

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