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Updated: May 31, 2025

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
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ERBB4可以选择性地放大TGF-β的转移前反应

Peihong Luo1, Huanyu Hong1, Baoling Zhang1

  • 1MOE Key Laboratory of Biosystems Homeostasis & Protection, and Zhejiang Provincial Key Laboratory of Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, Zhejiang 310058, China; Center for Life Sciences, Shaoxing Institute, Zhejiang University, Shaoxing, Zhejiang 321000, China; Cancer Center, Zhejiang University, Hangzhou, Zhejiang 310058, China.

Cell reports
|January 24, 2025
PubMed
概括

通过选择性地激活转化生长因子β (TGF-β) 信号,ERBB4促进癌症转移. 这涉及ERBB4酸化SMAD4,增强其DNA结合的转移性基因转录.

关键词:
CP: 癌症 癌症 癌症在EMT中,EMT是EMT.埃尔伯家族 (ERBB家族) 是一个家族.它们是SMAD蛋白质.在SMAD4/DPC4中使用.酸化的方法是:光化.信号传输 信号传输瘤发生的起源铁氨基酶酶的使用方法

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