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Updated: May 31, 2025

Transcriptome Profiling of In-Vivo Produced Bovine Pre-implantation Embryos Using Two-color Microarray Platform

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Published on: January 30, 2017

BuffExDb:基于网络的组织特异性基因表达资源,用于Bubalus bubalis中的育种和保护计划.

Naina Kumari^1,2, Samir Kumar³, Anupama Roy¹

¹Division of Agricultural Bioinformatics, ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, PUSA, New Delhi 110012, India.

Database : the journal of biological databases and curation

|January 24, 2025

概括

此摘要是机器生成的。

研究人员创建了BuffExDb,这是一个新的水牛基因表达数据库. 该资源有助于了解组织特异性基因,以改善水牛繁殖和保护工作.

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Published on: December 22, 2017

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Last Updated: May 31, 2025

Transcriptome Profiling of In-Vivo Produced Bovine Pre-implantation Embryos Using Two-color Microarray Platform

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Published on: January 30, 2017

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科学领域:

动物基因组学动物基因组学
生物信息学是一种生物信息学.
畜牧科学畜牧科学畜牧科学

背景情况:

畜牧业对全球可持续发展和减少贫困至关重要.
在亚洲,水牛在经济上至关重要,在牛奶生产方面超过了牛.
对于水牛来说,有限的基因组资源阻碍了特征增强,以增加产量.

研究的目的:

为了解决水牛基因组和转录基因组数据的稀缺问题.
开发一个全面的,用户友好的水牛基因表达数据库.
促进加强水牛繁殖和保护的研究.

主要方法:

从23个BioProjects中的438个生物样本中分析了2429个转录组.
利用生物信息学工具处理来自76种组织和细胞类型的数据.
开发了一个关系水牛表达式数据库 (BuffExDb),具有三层架构.

主要成果:

现在可以使用BuffExDb数据库 (http://46.202.167.198/buffex/).
该数据库允许轻松检索和功能注释组织特异性基因 (TSG).
使用Tau分数参数识别了TSG,并通过基因本体学丰富分析了它们的作用.

结论:

BuffExDb是第一个可导航和可过的水牛基因表达数据库.
提供了生物,功能和进化研究的基本数据.
支持未来的基因组研究,协会研究和水牛繁殖计划.