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对局部,低度尾粘膜性瘤的术后监测策略进行范围审查

Nebojša Oravec¹, Lloyd Mack¹, Dara Hallock²

¹Department of Surgery, University of Calgary Cumming School of Medicine, Calgary, Canada, T2N 1N4.

American journal of surgery

|January 24, 2025

概括

对局部,低度尾粘膜瘤 (LAMNs) 的术后监测缺乏关于生存益处的有力证据. 在LAMN切除后的监测策略中,建议以患者为中心的决策.

科学领域:

胃肠病学胃肠病学
手术瘤学手术瘤学
在瘤学瘤学.

背景情况:

关于切割后局部,低度尾粘膜性瘤 (LAMNs) 的最佳监测方案的数据有限.
尾粘膜性瘤代表了一组罕见的瘤,具有不同的恶性潜力.

研究的目的:

审查和综合现有的关于LAMNs手术后监测策略的文献.
评估与不同监测方法相关的复发率和无病存活率.

主要方法:

在四个数据库中进行了系统的文献搜索.
被收录的文章经过了两个独立审稿人的多阶段选 (标题,摘要,全文).
对包括的16项研究进行了数据提取和描述性统计分析.

主要成果:

该审查包括了16项研究,涉及1218名患者;监测持续时间差异很大 (0.1-294个月).
图像是最常见的监测方式 (48.7%).
观察到2.7% (31名患者) 的低复发率,复发时间从2.5到68个月不等. 五年生存率在93.5%至95.2%之间.

结论:

目前的证据并不强烈支持在切除后对局部LAMNs进行监测的生存优势.
对LAMN患者的监测决定应优先考虑个体患者的因素和偏好.
需要进一步的研究,以建立基于证据的LAMN监测指南.

关键词:

附录附录附录拉姆尼 (LAMN) 的意思低级别的低级别的粘菌性粘菌性粘菌性术后治疗术后治疗监督监督监督监督监督监督监督监督监督监督监督监督

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