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Atomic Force Microscopy

Atomic Force Microscopy

Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...

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Updated: May 31, 2025

Sub-nanometer Resolution Imaging with Amplitude-modulation Atomic Force Microscopy in Liquid

Sub-nanometer Resolution Imaging with Amplitude-modulation Atomic Force Microscopy in Liquid

Published on: December 20, 2016

使用振幅调制AFM对溶解力进行量化.

Simone Benaglia¹, Stefano Chiodini²

¹Department of Physics & Astronomy University of Manchester, Manchester M13 9PL UK; National Graphene Institute, University of Manchester, Manchester M13 9PL UK.

Journal of colloid and interface science

|January 24, 2025

概括

一种新的基于矩阵的力重建方法 (FRM) 用于振幅调制原子力显微镜 (AM-AFM) 准确捕获原子尺度的界面力. 这一进步增强了对固体-液体接口 (SLI) 和它们对纳米粒子相互作用等现象的影响的理解.

关键词:

部队重建重建的力量.固体 - 液体接口固体 - 液体接口三维原子力显微镜的三维原子力显微镜.

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Covalent Attachment of Single Molecules for AFM-based Force Spectroscopy

Covalent Attachment of Single Molecules for AFM-based Force Spectroscopy

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Atomic Force Microscopy Imaging and Force Spectroscopy of Supported Lipid Bilayers

Atomic Force Microscopy Imaging and Force Spectroscopy of Supported Lipid Bilayers

Published on: July 22, 2015

相关实验视频

Last Updated: May 31, 2025

Sub-nanometer Resolution Imaging with Amplitude-modulation Atomic Force Microscopy in Liquid

Sub-nanometer Resolution Imaging with Amplitude-modulation Atomic Force Microscopy in Liquid

Published on: December 20, 2016

Covalent Attachment of Single Molecules for AFM-based Force Spectroscopy

Covalent Attachment of Single Molecules for AFM-based Force Spectroscopy

Published on: March 16, 2020

Atomic Force Microscopy Imaging and Force Spectroscopy of Supported Lipid Bilayers

Atomic Force Microscopy Imaging and Force Spectroscopy of Supported Lipid Bilayers

Published on: July 22, 2015

科学领域:

表面科学是一门学科.
材料科学材料科学材料科学
体科学体科学体科学

背景情况:

介面溶解力对于材料科学和生物学的现象至关重要,但在分子层面上仍然不太了解.
三维原子力显微镜 (3D AFM) 提供了固体液体接口 (SLI) 的原子分辨率成像,但将数据转换为准确的力是具有挑战性的.

研究的目的:

为了比较标准振幅调制原子力显微镜 (AM-AFM) 力量重建方法 (FRM) 并确定它们的局限性.
为AM-AFM引入和验证一种基于数值矩阵的新型FRM,以克服SLI力量重建中的现有不准确性.

主要方法:

标准AM-AFM力量重建方法 (FRM) 的比较.
开发和验证一种基于数值矩阵的新型FRM,使用模拟和实验3D AFM数据在氧化物-水SLI.

主要成果:

这种基于矩阵的新型FRM可以在没有信息丢失的情况下,在原子尺度上重建完整的SLI交互.
这种方法独立于特定的AFM实验参数和力功能的形式.
该方法克服了标准FRM的局限性和不准确性.

结论:

开发的基于矩阵的FRM显著提高了SLI对接口属性的理解.
这种方法解锁了尖端样本相互作用中编码的全谱物理现象,影响着合体科学,纳米粒子相互作用和分子自我组装.