在青少年结核病的口腔表现:临床表现和组织病理学特征
A Skakodub1, M Osminina1, N Geppe1
1Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Russia.
Georgian medical news
|January 24, 2025
概括
口腔粘膜病变在青少年硬化症 (JS) 中很常见,早期出现并涉及缩性,缩性和血管变化. 这些发现突出了口腔腔的突出特点.
科学领域:
- 口腔病理学 口腔病理学
- 儿科风湿病学 儿科风湿病学
- 结合组织疾病 结合组织疾病
背景情况:
- 青少年硬化症 (JS) 是一种罕见的慢性结缔组织疾病,影响皮肤,软组织和潜在的内部器官.
- 在JS中,口腔的参与会导致显著的功能和化品问题,影响儿童早期的发育.
研究的目的:
- 为了研究口腔粘膜病变的组织形态学特征,在被诊断为青少年性硬化症的儿童中.
- 描述特定的病理变化及其在JS患者口腔组织中的患病率.
主要方法:
- 牙科检查和口腔粘膜的形态检查在39名青少年硬化症患者 (9名JSS,20名JSH).
- 分析包括组织损伤,血管化和免疫复合体沉积的组织病理学评估.
主要成果:
- 在100%的JS患者中观察到口腔粘膜损伤,在疾病过程中早期表现出来.
- 组织形态学发现包括缩和缩过程,异常的血管化,以及血管壁中的免疫复合物沉积 (C3,IgM,IgG) (72.63%).
- 口腔血管炎 (33.3%) 和血管病变 (52.63%) 是普遍存在的;确定了四个阶段的粘膜病变,并指出了二次传染性口腔炎.
结论:
- 口腔粘膜异常,包括缩性,缩性和血管变化,是青少年硬化症 (JSS和JSH) 的一致特征.
- 这些口腔病变的早期发病和渐进性质强调了儿童JS患者早期诊断和治疗的重要性.
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