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大型固体和固体占主导地位的甲状腺结节的热废除后的甲状腺功能障碍
Lanyan Qiu1, Yuqing Huang2, Yueyue Ge1
1Department of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
概括
固体甲状腺结节 (TNs) 的热切除除 (TA) 可以导致暂时的甲状腺功能障碍,特别是较大的结节. 建议在TA后的1-3个月内监测甲状腺激素,以有效管理.
科学领域:
- 内分泌学 在内分泌学.
- 干预性放射学 干预性放射学
背景情况:
- 热除 (TA) 是甲状腺结节 (TNs) 手术的替代方案.
- 在固体TN中,特别是大型TN中,TA对甲状腺功能的影响需要进一步研究.
研究的目的:
- 为了研究TA后甲状腺激素的变化,在患有固体主导TN的患者中.
- 为了确定后TA甲状腺功能障碍的危险因素.
主要方法:
- 招募的乙甲状腺患者具有固体主导的TN (≥80%的固体).
- 在TA之前评估TN体积,直径和细胞病理学.
- 使用微波或射频除进行TA.
- 测量甲状腺激素水平在各种间隔,直到12个月后TA.
主要成果:
- 在TA后1周,甲状腺功能率下降到70.1%,在12个月内恢复到100%.
- 观察到短期甲状腺功能障碍和亚临床甲状腺功能障碍,甲状腺激素和TSH水平发生变化.
- 较大的TN直径和较低的TSH基线水平是甲状腺功能障碍的独立风险因素.
结论:
- 在患有固体TNs的患者中,TA可能导致过渡性甲状腺功能障碍.
- 建议在TA后1周至3个月密切监测甲状腺激素水平,以控制潜在的功能障碍.
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