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Updated: May 31, 2025

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福莫诺丁可以通过抑制MAPK/PPAR-γ/NF-κB/ROS信号通路来缓解DSS诱导的大肠炎

Shen Cao1, Baojiang Lv2, Yi Tai1

  • 1Key Laboratory of Natural Resources of Changbai Mountain & Functional Molecules, Ministry of Education, Molecular Medicine Research Center, College of Pharmacy, Yanbian University, Yanji 133002, Jilin Province, China.

Toxicology and applied pharmacology
|January 24, 2025
PubMed
概括

福尔摩诺尼丁 (FMN) 通过抑制NLRP3炎症酶和NF-κB激活,有效治疗DSS诱导的大肠炎. 这种化合物减少炎症和氧化应激,为炎症性肠病 (IBD) 提供了潜在的治疗策略.

关键词:
作为一种单一的素.炎症性肠病是一种炎症性肠病.这就是MAPKK的意思.在 NF-κBB 中.在PPAR-γ中使用PPAR.这就是ROSOS ROS.

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