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Updated: May 31, 2025

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肝细胞CMPK2促进了与代谢功能障碍相关的脂肪肝炎的发展

Sitong Zhu1, Lei Liao2, Yi Zhong3

  • 1State Key Laboratory of Natural Medicines, China Pharmaceutical University, 210009, Nanjing, Jiangsu, China.

Journal of hepatology
|January 24, 2025
PubMed
概括

丁/尿素单酸酶2 (CMPK2) 是代谢功能障碍相关的脂肪肝炎 (MASH) 进展的关键驱动因素. 抑制CMPK2显著减少肝损伤和纤维化,为MASH提供了一个有希望的新治疗标.

关键词:
在CMPK2中使用.马什 (MASH) 是一个非常重要的产品.在NLRP3炎症酶体中,NLRP3炎症热致灭 (pyroptosis) 是一种致的过程.

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