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用于诊断的光流细胞计试验 - - 对试验实用性的讨论以及试验开发和验证的挑战

Vijaya Knight1

  • 1Department of Pediatrics, Section of Allergy and Immunology, University of Colorado School of Medicine, Immunopathology and Hematopathology Laboratory, Children's Hospital, 13123 East 16(th) Avenue, Aurora, CO 80045, United States of America.

Journal of immunological methods
|January 24, 2025
PubMed
概括

光流细胞计检测细胞信号的变化,并有研究应用. 试验验证方面的挑战阻碍了其临床诊断用途,特别是对于免疫的先天错误.

关键词:
测试验证的验证方法细胞信号传递 细胞信号传递流动细胞计量流动细胞计量免疫的先天错误 免疫的先天错误的流量 的流量

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Flow Cytometry01:23

Flow Cytometry

The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
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