在手术后,对于直肠癌幸存者来说,有什么新鲜事呢?
Arturo Cirera de Tudela1, Franco Marinello1, Eloy Espín Basany1
1Unidad de Cirugía Colorrectal, Servicio de Cirugía General y Digestiva, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.
Cirugia espanola
|January 24, 2025
概括
低前切除综合征 (LARS) 显著影响直肠癌幸存者,导致便失禁等问题. 本综述批判性地研究了管理LARS症状的治疗选择,因为目前还没有标准治疗方法.
科学领域:
- 结肠直肠手术 结肠直肠手术
- 手术瘤学手术瘤学
- 胃肠病学 胃肠病学
背景情况:
- 低前切除综合征 (LARS) 是直肠癌手术后经常出现的,被低估的并发症.
- LARS显著损害了患者的生活质量,症状包括便失禁和排泄功能障碍.
- 高达90%的接受低前肠直肠切除术的患者经历了LARS.
研究的目的:
- 批判性地审查治疗可能性,以管理直肠手术幸存的患者的症状.
- 为了解决LARS缺乏标准化治疗和患者选择的问题.
主要方法:
- 对LARS.现有的治疗方式的文献综述.
- 对导致LARS的多因素病因学的分析.
- 对治疗有效性和患者选择标准的批判性评估.
主要成果:
- LARS病因是多因素的,包括手术前的放射治疗,保护性静脉切除术,关损伤,神经损伤和结肠运动变化.
- 各种治疗方法对LARS症状显示出有效性,但缺乏标准方法.
- 在LARS管理中没有确定的患者选择模式.
结论:
- 有效管理LARS需要解决其复杂的病因.
- 需要进一步的研究,以建立标准化的治疗方案和LARS患者选择标准.
- 优化直肠癌幸存者的生活质量需要改进LARS管理策略.
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