西班牙裔种族与极度早产婴儿的结果之间的关系
Jane E Brumbaugh1, Carla M Bann2, Edward F Bell3
1Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN.
The Journal of pediatrics
|January 24, 2025
概括
与非西班牙裔黑人婴儿相比,西班牙裔母亲的婴儿在没有重大疾病的情况下的生存率较低. 西班牙裔儿童的神经发育障碍的几率也高于非西班牙裔白人儿童.
科学领域:
- 新生儿研究新生儿研究
- 围产期流行病学 围产期流行病学
- 在健康方面存在差异.
背景情况:
- 母亲的种族是婴儿健康结果的潜在决定因素.
- 了解早产婴儿生存和发病率的种族差异对于有针对性的干预至关重要.
研究的目的:
- 调查母亲的种族与极度早产婴儿在没有重大疾病的情况下的存活率之间的联系.
- 根据母亲的种族,分析两年的神经发育结果.
主要方法:
- 在怀孕27周之前出生的婴儿的潜在队列的二次分析 (2006-2020).
- 主要结局:在没有重大发病的情况下存活到出院 (定义为败血症,NEC,BPD,IVH,PVL,ROP).
- 结果根据母亲的种族 (西班牙裔,非西班牙裔黑人,非西班牙裔白人) 进行比较,并根据共变量进行调整.
主要成果:
- 与非西班牙裔黑人 (29%) 和非西班牙裔白人 (27%) 婴儿相比,西班牙裔婴儿在没有重大发病的情况下获得出院的生存率最低 (25%).
- 在没有重大发病率的情况下调整后的生存几率在西班牙裔与非西班牙裔黑人婴儿 (aOR 0.80) 中较低.
- 与非西班牙裔白人儿童相比,西班牙裔儿童在2岁时神经发育障碍的几率更高 (aOR 1.25).
结论:
- 与非西班牙裔黑人母亲的婴儿相比,西班牙裔母亲的婴儿在没有重大疾病的情况下生存的几率较低.
- 在西班牙裔和非西班牙裔白人母亲的婴儿之间观察到类似的生存几率,但没有重大发病率.
- 西班牙裔儿童面临神经发育障碍的可能性增加,突出了长期结果的种族差异.
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