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Updated: May 31, 2025

A Chromatin Assay for Human Brain Tissue
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染色体可访问性为人类大脑疾病的遗传病因提供了一个窗口

Jaroslav Bendl1, John F Fullard1, Kiran Girdhar1

  • 1Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

Trends in genetics : TIG
|January 24, 2025
PubMed
概括

遗传因素通过改变染色质可访问性的变化来改变基因表达,显著影响大脑疾病. 先进的基因组工具有助于绘制这些变化,指导未来的基因调节疗法.

关键词:
脑部疾病 脑部疾病在这种情况下,染色染色素基因表达的基因表达方式神经基因组学 神经基因组学精准医学是一门精准医学.

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