相关实验视频

Updated: Jun 26, 2026

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data
14:27

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data

Published on: June 26, 2013

15.6K

识别亨廷顿病轨迹中的时间模式,使用基于多模式数据的动态时间扭曲集群

Alexia Giannoula1, Audrey E De Paepe2,3, Ferran Sanz2

  • 1Research Group on Integrative Biomedical Informatics (GRIB), Department of Medicine and Life Sciences (MELIS), Universitat Pompeu Fabra, Hospital del Mar Research Institute, Barcelona, Spain. alexia.giannoula@upf.edu.

Scientific reports
|January 24, 2025
PubMed
概括

这项研究引入了一种新的数据挖掘方法,使用动态时间曲线 (Dynamic Time Warping) 来聚合患者的健康数据,揭示了个性化医疗的独特时间模式. 它有助于通过分析个体变异性来分层亨廷顿病患者.

关键词:
纵向队列分析 纵向队列分析多模式现实世界数据.患者的分层是患者的分层.精准医学是一门精准的医学.时间分析时间分析.没有监督的集群.

更多相关视频

Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington's Disease09:06

Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington's Disease

Published on: June 9, 2018

12.1K
Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

15.2K

相关概念视频

Huntington Disease l: Introduction01:21

Huntington Disease l: Introduction

Huntington disease or HD is a progressive, fatal neurodegenerative disorder inherited in an autosomal dominant pattern.PathophysiologyIt is caused by expansion of the CAG trinucleotide repeat in the HTT gene on chromosome 4 (4p16.3), producing an abnormal huntingtin protein with an expanded polyglutamine tract. This misfolded protein disrupts cellular function, leading to neuronal death. Normal alleles have ≤26 repeats, 27–35 are intermediate (risk of expansion), 36–39 show reduced penetrance,...