空气污染物与喘儿科患者血细胞计数之间的关联:一项追溯观察性研究
Kuo-Chen Huang1, Hsiu-Yung Pan1, Ting-Min Hsieh2
1Department of Emergency Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, No. 123, Dapi Road, Niaosong Township, Kaohsiung County 833, Kaohsiung City, Taiwan.
BMC public health
|January 25, 2025
概括
包括PM2.5和PM10在内的空气污染与患有喘的儿童中绝对中性粒细胞数 (ANC),乙氨基酸细胞数和血小板数的增加有关. 这些发现凸显了环境因素对儿科呼吸系统健康的影响.
科学领域:
- 环境健康 环境健康
- 儿科肺病学 儿科肺病学
- 血液学 血液学 血液学
背景情况:
- 喘是儿童普遍存在的呼吸系统疾病.
- 空气污染是儿童喘的一个已知的危险因素.
- 空气污染对儿童喘患者血细胞计数的具体影响尚不清楚.
研究的目的:
- 研究暴露于环境空气污染物和喘儿童血细胞计数之间的关联.
- 为了确定特定的空气污染物是否与绝对中性粒细胞数 (ANC),氨酸细胞数和血小板数的变化相关.
主要方法:
- 从2007年到2018年进行了一项回顾性观察性研究.
- 分析了来自17岁的喘急诊室患者的数据.
- 血液细胞计数 (ANC,乙酸盐,血小板) 和空气污染物度 (PM2.5,PM10,SO2,NO2,O3) 被提取并相关联.
主要成果:
- 增加的PM2.5,PM10,NO2,SO2和O3水平与更高的ANC有关.
- PM2.5,PM10和SO2与乙氨基酸细胞数量呈正相关性.
- PM2.5和PM10与血小板数量有积极的关联.
- 即使调整了其他污染物,特别是PM2.5和PM10,这些关联仍然很重要.
结论:
- 颗粒物 (PM2.5,PM10) 和二氧化 (NO2) 独立地与儿科喘患者的ANC升高有关.
- PM2.5和PM10与血小板数量的增加有积极联系.
- 这些发现强调了空气质量与喘儿童的血液学参数之间的显著关系.
相关概念视频
Asthma-I: Introduction
2.6K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.6K
Asthma-II: Pathophysiology and Classification
2.6K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
2.6K
Lung Capacity
49.2K
The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
49.2K
Asthma: Pathogenesis and Management
343
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
343
Asthma-III: Symptoms and Complications
2.5K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
2.5K
Factors Affecting Pulmonary Ventilation
1.1K
Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
1.1K


