肥胖指标与高脂血症患者死亡率之间的关联:来自NHANES 2003-2018年的证据

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Yiheng Zhang¹, Yajun Yao^2,3

¹Department of Infectious Diseases and Hepatology, The Second Hospital of Shandong University, Jinan, China.

Lipids in health and disease

|January 25, 2025

概括

在患有高脂血症的成年人中,体重调整后的腰部指数 (WWI) 显示出与整体和心血管疾病 (CVD) 死亡率的增加有线联系. 其他肥胖指标,如BMI和腰与身高比率 (WHtR),与死亡率有U形关系.

科学领域:

心血管健康心血管健康
代谢障碍代谢障碍代谢障碍
肥胖问题研究研究

背景情况:

肥胖是代谢功能障碍和心血管疾病 (CVD) 的重要危险因素.
超脂血是心血管疾病的一个关键可修改的危险因素.
肥胖指标与超脂血症美国成年人死亡率之间的关联以前不清楚.

研究的目的:

调查肥胖指标与美国成年人患有高脂血症的整体和心血管疾病死亡率之间的关系.
为了比较不同肥胖指标对死亡率结果的预测能力.

主要方法:

利用了来自国家健康和营养检查调查 (NHANES) (2003-2018) 的数据,其中包括12785名患有高脂血症的参与者.
评估的肥胖指标:体重调整的腰指数 (WWI),腰与身高的比率 (WHtR) 和体重指数 (BMI).
使用加权考克斯回归,限制立方线 (RCS) 和ROC曲线分析来评估关联和预测准确性.

主要成果:

第一次世界大战的增加与更高的整体和心血管疾病死亡率有关 (P < 0.05).
体重指数和WHtR显示出与死亡率的U形关系.
第一次世界大战证明了与死亡率的线性正相关性,以及对整体和心血管疾病死亡的BMI和WHtR的优越预测能力.

结论:

在患有高脂血症的美国成年人中,第一次世界大战显示出与死亡率的线性相关性,而BMI和WHtR显示出U形模式.
与BMI和WHtR相比,第一次世界大战是高脂血症个体死亡率的更有效预测因素.
这些发现为管理高脂血症及其相关死亡风险提供了新的目标.

关键词:

超脂血症是因为高脂血症死亡率死亡率死亡率尼汉斯 (NHANES) 是一个名人.肥胖问题肥胖问题体重调整后的腰部指数

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