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Updated: May 31, 2025

Glomerular Outgrowth as an Ex Vivo Assay to Analyze Pathways Involved in Parietal Epithelial Cell Activation
06:39

Glomerular Outgrowth as an Ex Vivo Assay to Analyze Pathways Involved in Parietal Epithelial Cell Activation

Published on: August 19, 2020

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瘤和非瘤的焦点细分细胞凝结症:临床特征,病因学和哥伦比亚分类

Gabriel Figueiredo1, Luis Yu1, Lectícia Barbosa Jorge1

  • 1Nephrology Department, Hospital das Clínicas of São Paulo, São Paulo 05403-900, Brazil.

Diagnostics (Basel, Switzerland)
|January 25, 2025
PubMed
概括

没有脏综合征的焦点细分型血小板硬化 (FSGS) 患者与脏综合征患者相比,表现出类似的不良结局. 达到每天1.5克以下的蛋白尿是非性FSGS更好的生存的关键.

关键词:
焦点细分型淋巴结核硬化功能衰竭 功能衰竭是什么?鼻性综合征是什么意思蛋白质尿症是一种蛋白质尿症.

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Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice09:43

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Renal Corpuscle

The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
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Glomerular Filtration

The filtration membrane in the renal system is a highly specialized structure essential for filtering blood. It consists of glomerular capillaries and podocytes, forming a selective barrier that permits the passage of water and small solutes while restricting most plasma proteins and blood cells.
Components of the Filtration Membrane
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Glomerular Filtration Rate and its Regulation

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The renal tubule is divided into three parts: the proximal convoluted tubule (PCT), the Loop of Henle (LOH), and the distal convoluted tubule (DCT).
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...
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Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
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