衰老对隔膜功能和最大吸气压的影响:一个横截面超声波研究
Toru Yamada1, Taro Minami2,3, Takahiro Shinohara1
1Department of General Medicine, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Bunkyo-ku, Tokyo 113-8510, Japan.
Diagnostics (Basel, Switzerland)
|January 25, 2025
概括
衰老会增加隔膜厚度,但不会增加其外出,从而影响呼吸能力. 隔膜外,而不是厚度,与最大吸入压力相关,表明它.
科学领域:
- 老年学和呼吸系统生理学
- 诊断成像和超声波的使用.
背景情况:
- 衰老对隔膜功能的影响仍然不完全理解.
- 超声波越来越多地用于评估呼吸道肌肉功能.
研究的目的:
- 为了研究衰老与隔膜超声波参数之间的关联:厚度,加厚分数 (TF) 和隔膜外流 (DE).
- 探索这些隔膜参数与最大吸入压力 (MIP) 之间的关系.
主要方法:
- 这项前性研究涉及4个日本机构的230名成年志愿者和门诊患者.
- 隔膜厚度,TF和DE使用超声波测量.
- 多变量回归分析根据年龄,性别,身高,BMI和并发症进行调整.
主要成果:
- 与非老年人相比,老年人表现出更厚的隔膜和更低的TF;DE没有显著差异.
- 年龄与隔膜厚度有积极关联,但在调整后没有TF或DE.
- MIP与DE正相关,但与隔膜厚度或TF无关.
- 年龄与MIP负相关,独立于隔膜参数.
结论:
- 隔膜加厚随着年龄的增长而发生,但这和TF与MIP无关.
- 隔膜外流 (DE) 是与MIP相关的关键超声波参数.
- 与年龄相关的MIP下降独立于隔膜厚度和TF的变化,突出显示了DE对于评估老年人呼吸肌肉强度的重要性.
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