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Updated: May 31, 2025

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基于转录组学和蛋白质组学,探索大鼠铁过载引起的肝损伤的机制

Yujia Shu1,2, Xuanfu Wu1,2, Dongxu Zhang1,2

  • 1Key Laboratory of Animal Physiology and Biochemistry, Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.

Biology
|January 25, 2025
PubMed
概括

过量的铁可以通过增加氧化应激导致肝损伤. 抑制Lnc286.2可以增强HO-1,减少脂质过氧化,并防止铁过载损伤.

关键词:
铁过载是什么?铁过载是什么?肝脏损伤 肝脏损伤是什么?蛋白质组学 蛋白质组学翻译学 翻译学 翻译学 翻译学

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Liver Physiology01:30

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The liver, an essential organ in the human body, performs over 200 vital functions that can be broadly categorized into metabolic, hematological, endocrine regulation, and bile production.
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of  70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
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