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Updated: May 31, 2025

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与疾病相关的多巴胺受体D2变体表现出功能性后果,这取决于不同的异构三维G蛋白子单元组合

Nele Niebrügge1, Olga Trovato1, Roman Praschberger2

  • 1Institute of Pharmacology, Medical University of Innsbruck, 6020 Innsbruck, Austria.

Biomedicines
|January 25, 2025
PubMed
概括

多巴胺受体D2 (DRD2) 的突变会导致功能增益的表型,影响G蛋白信号传递,导致运动障碍. 表达的特定G蛋白复合体显著改变了受体.

关键词:
在GPCRs中,GPCRs是指GPCR.多巴胺受体的多巴胺受体运动障碍 运动障碍

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