相关实验视频

Updated: May 31, 2025

Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection

Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection

Published on: June 5, 2021

患有SARS-CoV-2的患者的红细胞病理学

Sona Hakobyan¹, Lina Hakobyan¹, Liana Abroyan¹

¹Laboratory of Cell Biology and Virology, Institute of Molecular Biology of NAS RA, Yerevan 0014, Armenia.

|January 25, 2025

概括

血液学标志物如血清费里,C反应蛋白 (CRP) 和异细胞分裂症表明严重的冠状病毒疾病 (COVID-19). 红细胞中血红蛋白吸收谱的改变也与SARS-CoV-2感染的不良结果相关.

科学领域:

血液学血液学血液学
病毒学病毒学
病理学病理学病理学

背景情况:

严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 感染与血液学疾病有关.
冠状病毒感染中的红细胞病理学提供了对疾病严重程度和进展的见解.

研究的目的:

审查和分析SARS-CoV-2患者的红细胞病理学.
专注于不同疾病严重程度组的临床和实验室发现.

主要方法:

患者被分为四组:常规,严重,低和和红细胞母细胞.
临床实验室调查包括例行研究和扫描显微光谱测试,以检测血红蛋白 (Hb) 谱.
测量了420nm的红细胞计数和Hb吸附光谱.

主要成果:

在~30%的SARS-CoV-2患者中检测到红细胞,主要是在重症组.
血清费里丁,C反应蛋白 (CRP) 和异细胞分裂与疾病严重程度有很强的相关性.
在Hb吸附光谱的显著变化,在严重的情况下,在420nm时吸收率增加.

结论:

血清费里,CRP,无细胞化和420nm的改变Hb吸收的升高与SARS-CoV-2的不良结果有关.
血液学参数可以作为疾病严重程度和病毒感染预后的标志物.

关键词:

在 COVID-19 疫情中,红色母细胞体的发生.血红蛋白吸附吸附是血红蛋白的吸附.显微光谱光度测量 (microspectrophotometry) 是一种使用微光谱光度测量的方法.红细胞是血液中的红细胞.

更多相关视频

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Published on: December 19, 2020

Visualization of SARS-CoV-2 using Immuno RNA-Fluorescence In Situ Hybridization

Visualization of SARS-CoV-2 using Immuno RNA-Fluorescence In Situ Hybridization

Published on: December 23, 2020

相关概念视频

Disorders of Erythrocytes

Disorders of Erythrocytes

Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...

Erythropoiesis

Erythropoiesis

Red blood cells (RBCs) transport oxygen to all body tissues. These cells survive only for 120 days and then need to be replenished. Erythropoiesis is the process of RBC production. In healthy individuals, erythropoiesis ensures all tissues are amply supplied with oxygen. In addition, blood loss due to injury leads to a drop in the physiological oxygen level that will cause erythropoiesis. Any defect in erythropoiesis leads to several physiological disorders, including thalassemia, anemia,...

Pneumonia II: Pathophysiology

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps: