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在儿科急诊室的抗菌药物管理:一个观察性前后研究

Erika Silvestro¹, Ilaria Mussinatto², Antonia Versace³

¹Infectious Diseases Unit, Department of Pediatrics, Regina Margherita Children's Hospital, A.O.U. Città della Salute e della Scienza di Torino, 10126 Turin, TO, Italy.

Children (Basel, Switzerland)

|January 25, 2025

概括

一个教育性抗微生物管理计划显著改善了儿科急诊室的抗生素适用性,提高了儿童常见感染的治疗策略.

科学领域:

儿童传染病儿童传染病
抗微生物耐药性抗微生物耐药性
公共卫生公共卫生

背景情况:

抗菌素耐药性 (AMR) 是一个日益增长的全球健康威胁.
抗微生物药物管理计划 (ASP) 对于打击AMR至关重要.
儿科紧急情况需要针对抗生素管理的具体策略.

研究的目的:

评估在儿科急诊室 (ED) 处方抗生素的教育干预措施的有效性.
评估抗菌药物管理计划对儿科患者抗生素适用性的影响.

主要方法:

采用了前后观察性研究设计.
实施了包括每周会议和数字指南在内的教育干预.
在干预之前和之后,对抗生素处方的适当性 (分子,剂量,持续时间) 进行了审计.

主要成果:

观察到整体抗生素充足性的显著改善 (13%的干预前比43%的干预后,p <0.001).
关键方面,如对抗生素的需求,频谱充足性和分子选择,也显示出显著的改善.
对于常见的儿科感染,如耳炎和喉炎,第一选择药物的处方增加了.

结论:

抗菌药物管理计划在优化儿科ED的抗生素使用方面是有效的.
教育干预可以成功地提高儿童急救护理中的抗生素适用性.
针对性ASP对于治疗儿科患者的AMR至关重要.

关键词:

抗微生物药物管理管理儿科急救部门的儿童急救部门.儿科传染病儿童传染病

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