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相关概念视频

Synthesis and Regulation of Thyroid Hormones01:20

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
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Functions of Thyroid Hormones01:18

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The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
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相关实验视频

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Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
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新生儿甲状腺刺激激素参考间隔在多民族人口.

Hery Priyanto1, Fauqa Arinil Aulia2, Hartono Kahar2

  • 1Clinical Pathology Sub-Specialization Program, Department of Clinical Pathology Dr. Soetomo Academic Hospital, Faculty of Medicine Universitas Airlangga, Surabaya 60132, Indonesia.

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概括

这项研究为印尼新生儿建立了关键的甲状腺刺激激素 (TSH) 参考间隔,考虑到年龄,性别和种族. 这些发现对于准确的新生儿查和诊断在当地人口中至关重要.

关键词:
儿童健康 儿童健康干燥的血液斑点 干燥的血液斑点参考时间间隔的参考时间间隔.甲状腺刺激激素激素是什么

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科学领域:

  • 新生儿查和新生儿诊断
  • 内分泌学 在内分泌学.
  • 公共卫生 公共卫生

背景情况:

  • 准确的甲状腺刺激激素 (TSH) 参考间隔对于新生儿健康至关重要.
  • 现有的TSH参考间隔可能不准确地反映全球多样化的人口,包括印尼人.
  • 这项研究解决了在印度尼西亚需要局部TSH参考范围的需求.

研究的目的:

  • 为印尼新生儿建立精确的甲状腺刺激激素 (TSH) 参考间隔.
  • 根据新生儿年龄组,性别,妊娠年龄和种族背景来定制这些间隔.
  • 提高印尼新生儿查和诊断的准确性.

主要方法:

  • 利用了在2022年1月至2023年12月期间收集的新生儿TSH值.
  • 通过根据性别,妊娠年龄和族群划分数据来建立TSH参考间隔.
  • 在各种新生儿年龄子组中分析了TSH值.

主要成果:

  • 通过性别,妊娠年龄和种族群体 (p <0.05) 观察到TSH参考间隔的显著差异.
  • 与女性相比,男性新生儿的TSH参考间隔较高.
  • 在晚期和术后的妊娠年龄类别中,观察到更高的TSH参考间隔.
  • 马杜雷斯族群的TSH参考间隔的上限较高.

结论:

  • 专门为印尼新生儿群体开发了一套局部化的TSH参考间隔.
  • 这些量身定制的间隔对于提高印尼新生儿查的诊断准确性至关重要.
  • 这些发现强调了在建立临床参考范围时考虑人口因素的重要性.