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新生儿甲状腺刺激激素参考间隔在多民族人口
Hery Priyanto1, Fauqa Arinil Aulia2, Hartono Kahar2
1Clinical Pathology Sub-Specialization Program, Department of Clinical Pathology Dr. Soetomo Academic Hospital, Faculty of Medicine Universitas Airlangga, Surabaya 60132, Indonesia.
Children (Basel, Switzerland)
|January 25, 2025
概括
这项研究为印尼新生儿建立了关键的甲状腺刺激激素 (TSH) 参考间隔,考虑到年龄,性别和种族. 这些发现对于准确的新生儿查和诊断在当地人口中至关重要.
科学领域:
- 新生儿查和新生儿诊断
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 准确的甲状腺刺激激素 (TSH) 参考间隔对于新生儿健康至关重要.
- 现有的TSH参考间隔可能不准确地反映全球多样化的人口,包括印尼人.
- 这项研究解决了在印度尼西亚需要局部TSH参考范围的需求.
研究的目的:
- 为印尼新生儿建立精确的甲状腺刺激激素 (TSH) 参考间隔.
- 根据新生儿年龄组,性别,妊娠年龄和种族背景来定制这些间隔.
- 提高印尼新生儿查和诊断的准确性.
主要方法:
- 利用了在2022年1月至2023年12月期间收集的新生儿TSH值.
- 通过根据性别,妊娠年龄和族群划分数据来建立TSH参考间隔.
- 在各种新生儿年龄子组中分析了TSH值.
主要成果:
- 通过性别,妊娠年龄和种族群体 (p <0.05) 观察到TSH参考间隔的显著差异.
- 与女性相比,男性新生儿的TSH参考间隔较高.
- 在晚期和术后的妊娠年龄类别中,观察到更高的TSH参考间隔.
- 马杜雷斯族群的TSH参考间隔的上限较高.
结论:
- 专门为印尼新生儿群体开发了一套局部化的TSH参考间隔.
- 这些量身定制的间隔对于提高印尼新生儿查的诊断准确性至关重要.
- 这些发现强调了在建立临床参考范围时考虑人口因素的重要性.
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