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Updated: May 31, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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合成和抗癌活性在 Vitro 的 Synephrine 衍生物的合成和抗癌活性

Ekaterina M Zhidkova1, Evgeniya S Oleynik2, Ekaterina A Mikhina2

  • 1Department of Chemical Carcinogenesis, Institute of Carcinogenesis, N.N. Blokhin National Medical Research Center for Oncology, Kashirskoe Shosse 24-15, Moscow 115478, Russia.

Biomolecules
|January 25, 2025
PubMed
概括

研究人员开发了新型的synephrine衍生物作为癌症治疗的潜在选择性葡萄糖皮质体受体激动剂 (SEGRA). 一种衍生物在白血病和淋巴瘤细胞中显示出有前途的抗癌活性,为药物开发提供了新的途径.

关键词:
细胞毒性 细胞毒性血液学的恶性瘤.选择性葡萄糖皮质体受体激动剂.合成synephrine衍生物的合成虚拟对接是虚拟的对接.

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