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Updated: May 31, 2025

Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity
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潘杜拉丁A通过抑制NF-κB通路来抑制TNFα刺激的内皮细胞激活,从而抑制TNFα刺激的内皮细胞激活

Kriangkrai Kiatsoonthon1, Nitchakarn Phimthong1,2, Saranyapin Potikanond1

  • 1Department of Pharmacology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.

Biomolecules
|January 25, 2025
PubMed
概括

潘杜拉丁A (PA) 抑制瘤亡因子-α (TNF-α) 诱导的内皮激活和单细胞粘附,这是动脉样硬化发展的关键步骤. 帕向NF-κB通路,这表明在预防动脉样硬化方面具有潜在的治疗益处.

关键词:
在 ICAM-1 中.在 NF-κBB 中.这就是TNF-alpha.这是一个VCAM-1系统.动脉样硬化 动脉样硬化内皮细胞激活的过程一个单细胞的粘附.潘杜拉丁A是一种

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