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Updated: May 31, 2025

Thermodynamics of Membrane Protein Folding Measured by Fluorescence Spectroscopy
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蛋白质二次结构展开中的动态同位素效应:作为模型的Beta-Sheet多糖氨酸二次体的计算

Alexey O Yanshin1,2, Vitaly G Kiselev1,2, Alexey V Baklanov1

  • 1Institute of Chemical Kinetics and Combustion SB RAS, 3 Institutskaya Street, Novosibirsk 630090, Russia.

Biomolecules
|January 25, 2025
PubMed
概括

重同位素替代,特别是H/D,通过加强链间的键,显著稳定了蛋白质的二次结构. 这种效应即使在中等长的蛋白质链中也是显著的,为蛋白质折叠动态提供了洞察力.

关键词:
完全松散的过渡状态.键是一种键.动态同位素效应的动力效应.多聚甘氨酸二聚体的二聚体.蛋白质蛋白质是蛋白质蛋白质的组成部分.在展开的展开.

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