关氨酸四重复拓的免疫刺激作用作为CpGOligodeoxynucleotides的支架

Soumitra Pathak1,2, Nguyen Bui Thao Le1,2, Taiji Oyama3,4

  • 1Research Center for Macromolecules and Biomaterials, National Institute for Materials Science (NIMS), 1-2-1 Sengen, Tsukuba 305-0047, Japan.

Biomolecules
|January 25, 2025
PubMed
概括

瓜四重复 (G4) 形成酸-瓜寡氧核酸 (CpG ODNs) 显示出改善的稳定性和免疫反应. 平行G4 CpG ODN提供了最好的潜力作为疫苗辅助剂,由于增强的稳定性和细胞吸收.

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