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Updated: May 31, 2025

Gene Digital Circuits Based on CRISPR-Cas Systems and Anti-CRISPR Proteins
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准影响Actinoplanes sp. 的阿卡尔生物合成的转录调节剂. SE50/110 使用CRISPRi沉默器进行沉默

Saskia Dymek1, Lucas Jacob1, Alfred Pühler2

  • 1Microbial Genomics and Biotechnology, Center for Biotechnology, Bielefeld University, 33615 Bielefeld, Germany.

Microorganisms
|January 25, 2025
PubMed
概括

采用CRISPR干扰 (CRISPRi) 技术,确定了Actinoplanes sp.中阿卡尔生物合成的调节剂. 在SE50/110.0. 这种方法成功地确定了11个调节糖生产的基因,其中7个降低了糖的产量,4个提高了产量.

关键词:
在Actinoplanes中表演.这就是CRISPR干扰的原因.克里斯普里是指克里斯普里.这种药物是阿卡尔糖 (acarbose).图书馆 图书馆 图书馆 是一个转录调节器是指转录调节器.

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