怀孕并发症和结果在肥胖妇女怀孕期糖尿病
Gitana Ramonienė1, Laura Malakauskienė1, Eglė Savukynė1
1Department of Obstetrics and Gynaecology, Medical Academy, Lithuanian University of Health Sciences, A. Mickevicius St. 7, 44307 Kaunas, Lithuania.
Medicina (Kaunas, Lithuania)
|January 25, 2025
概括
患有妊娠糖尿病 (GDM) 的肥胖女性面临更高的妊娠并发症风险,包括高血压和剖腹产. 他们的新生儿也更容易发生宏观症和较低的Apgar分数.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 内分泌学 在内分泌学.
背景情况:
- 肥胖在怀孕期间越来越令人担忧,可能会加剧诸如妊娠期糖尿病 (GDM) 等疾病.
- 了解肥胖对GDM结果的影响对于改善母亲和新生儿健康至关重要.
研究的目的:
- 为了比较肥胖和正常体重的女性与GDM的妊娠和分娩并发症.
- 评估新生儿结局,包括出生时的体重和状况,与母亲怀孕前的肥胖有关.
主要方法:
- 一项回顾性研究分析了来自第三级推中心出生登记册的583名患有GDM和单胎怀孕的女性的数据 (2019年).
- 女性被分为肥胖 (BMI ≥30 kg/m2; n=202) 和正常体重 (BMI 18.5-24.9 kg/m2; n=381) 的两组.
- 使用IBM SPSS统计和MS Excel进行了统计分析,p < 0.05被认为是显著的.
主要成果:
- 与正常体重的同行相比,患有GDM的肥胖女性的禁食和OGTT血糖水平显著增加.
- 在肥胖妇女中观察到较高的初级高血压,高血压障碍,妊娠胆固醇,多水,诱导分娩和剖腹产 (特别是紧急分娩) 的发生率.
- 产后并发症,如 Dystocia 和胎儿痛苦,以及新生儿宏观症和1分钟和5分钟的较低的Apgar分数,在肥胖母亲的新生儿中更为频繁.
结论:
- 在怀孕前的肥胖显著增加了GDM妇女怀孕和分娩并发症的风险和严重程度.
- 在GDM中,肥胖与新生儿不良结果有关,突出了针对性干预的需要.
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