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Updated: May 31, 2025

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
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优化SARS-CoV-2 Mpro 抑制剂通过基于结构的多层次虚拟查方法

Lanlan Jing1, Fabao Zhao1, Lin Zheng1

  • 1Key Laboratory of Chemical Biology (Ministry of Education), Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.

International journal of molecular sciences
|January 25, 2025
PubMed
概括

研究人员通过选针对Mpro酶的化合物开发了新的潜在抗SARS-CoV-2药物. 化合物A9显示出强烈的抗病毒活性,使其成为未来针对COVID-19的药物开发的有希望的候选人.

关键词:
在 COVID-19 疫情中,这就是SARS-CoV-2病毒.主要蛋白质酶的主要蛋白质酶虚拟选 虚拟选 虚拟选

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