SiO2纳米颗粒与酸和单乙胺的声化学功能化及其对抗菌活性显著的影响
Iván Toledo-Manuel1, Marissa Pérez-Alvarez1, Gregorio Cadenas-Pliego1
1Centro de Investigación en Química Aplicada (CIQA), Blvd. Ing. Enrique Reyna H. No. 140, Saltillo 25294, Coahuila, Mexico.
Materials (Basel, Switzerland)
|January 25, 2025
概括
用酸 (CA) 或单乙胺 (MEA) 功能化纳米粒子 (SiO2 NPs) 增强了它们的抗菌活性. SiO2-CA NPs表现出优异的分散性和99.99%的大肠杆菌和黄金杆菌的抑制.
科学领域:
- 材料科学 材料科学 材料科学
- 纳米技术纳米技术
- 微生物学 微生物学
背景情况:
- 纳米粒子 (NP) 通过与微生物细胞相互作用,表现出强大的抗菌特性.
- 在各种介质中,NP聚合可以阻碍它们的抗微生物有效性和稳定性.
- 用有机配体进行表面功能化是增强NP分散和抗菌活性的关键策略.
研究的目的:
- 研究二氧化纳米颗粒 (SiO2 NPs) 与酸 (CA) 和单乙胺 (MEA) 的声化学功能化.
- 评估这些有机配体对SiO2NP的稳定性,分散性和抗菌活性 (AA) 的影响.
主要方法:
- 用CA和MEA功能化的SiO2NP的声化学合成.
- 使用X射线衍射 (XRD),X射线光电子光谱 (XPS),热重力测量分析 (TGA),里埃变换红外光谱 (FTIR),RAMAN光谱,扫描电子显微镜 (SEM),传输电子显微镜 (TEM) 和泽塔电位测量的特征.
- 抗菌活性测定针对金黄色葡萄球菌和大肠杆菌.
主要成果:
- 用XRD,XPS,FTIR和RAMAN光谱学证实了功能化,这表明了碳氧基和氨基基团的存在.
- 与MEA (SiO2-MEA NPs) 功能化的SiO2 NPs显示了较高的有机配体含量 (34.42%) 与CA (SiO2-CA NPs) (28.0%) 相比.
- 功能化显著改善了NP分散,并防止了聚合,正如SEM,TEM和zeta潜力所证明的那样.
- SiO2-CA NPs表现出最高的抗菌活性,在200ppm时达到99.99%的大肠杆菌和金黄色杆菌的抑制.
- 即使在高度 (1200 ppm) 中,也保持了高的抗菌疗效.
结论:
- 声化学功能化是一种有效的方法,可以增强SiO2NP的分散和抗菌特性.
- 酸功能化产生SiO2NP,对常见的细菌菌株具有优越的抗菌性能.
- 这些功能化的NP在需要强大和稳定的生物杀伤剂的应用中表现有希望,例如海洋涂料.
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