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Updated: May 31, 2025

Evaluation of the Storage Stability of Extracellular Vesicles
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细胞外囊作为穿越血脑屏障的工具,用于治疗溶酶体储存疾病

Giovanni Lerussi1, Verónica Villagrasa-Araya1,2,3, Marc Moltó-Abad1,2

  • 1Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT), Vall d'Hebron Institute of Research (VHIR), 08035 Barcelona, Spain.

Life (Basel, Switzerland)
|January 25, 2025
PubMed
概括

细胞外囊泡 (EVs) 在治疗中枢神经系统 (CNS) 溶酶体储存障碍 (LSDs) 方面表现有前途. 这些工程EV可以穿越血脑屏障 (BBB) 来提供治疗药物,克服当前治疗方法的局限性.

关键词:
血脑屏障 血脑屏障 血脑屏障 血脑屏障药物输送是药物输送的过程.酶替代疗法是一种酶替代疗法.外基因组是外基因组的组成部分.细胞外囊泡中的细胞外囊泡.lysosomal 储存疾病 lysosomal 储存疾病神经退行性疾病的神经退行性疾病提供蛋白质的蛋白质输送.

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