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在一般病房的败血症患者中进行液体复苏和初始管理
Sung Won Chang1, Juwhan Choi1, Jee Youn Oh1
1Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul 08308, Republic of Korea.
Life (Basel, Switzerland)
|January 25, 2025
概括
医院的败血症管理尚不清楚. 这项研究发现,30毫升/千克或以上的液体复苏与重症监护室 (ICU) 死亡率无关,尽管需要持续置换疗法 (CRRT) 的患者较少.
科学领域:
- 关键护理医学 关键护理医学
- 内部医学 内部医学
- 紧急医疗 紧急医疗
背景情况:
- 医院呈现性败血症的最佳管理需要进一步调查.
- 了解液体复苏对临床结果的影响至关重要.
研究的目的:
- 检查一般病房的初始败血症管理.
- 评估液体复苏量与临床结果之间的关联.
- 为了确定影响败血症患者体液复苏的因素.
主要方法:
- 在一般病房的败血症引起的低血压患者的回顾性研究.
- 根据液体复苏进行分组:少于30 (<30毫升/公斤) 和超过30 (≥30毫升/公斤).
- 多变量后勤回归分析以确定关联.
主要成果:
- 平均液体体积为9.2毫升/千克 (少于30) 和35.9毫升/千克 (超过30).
- 在重症监护室 (ICU) 的死亡率相似 (43.0%对45.5%).
- 连续置换疗法 (CRRT) 在不到30岁的患者中使用了27.8%,在30岁以上的患者中使用了0%. 液体复苏≥30mL/kg与ICU死亡率无关.
- 低体重和缩血压预测了更高的液体复苏量.
结论:
- 大多数入院的败血症患者接受的液体复苏量低于推的30毫升/公斤.
- 液体复苏量≥30mL/kg与ICU死亡率没有显著的关联.
- 较低的体重和静心血压是与接受更多液体复苏相关的因素.
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