草药中的生物活性化合物和化学元素的评价:在超声波辅助提取中,基于胆化的深度修养溶剂的有效性

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Aleksandra Szydłowska-Czerniak¹, Agnieszka Kowaluk², Michał Strzelec²

¹Department of Analytical Chemistry and Applied Spectroscopy, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, 87-100 Toruń, Poland.

Molecules (Basel, Switzerland)

|January 25, 2025

概括

以胆化物为基础的深溶剂被测试用于从草药中提取抗氧化剂. 胆化物:马龙酸显示出高潜力,但绿色溶剂提取的抗氧化剂比常规酒精少.

科学领域:

绿色化学和溶剂提取.
植物化学和天然产品分析.
草药和营养保健品. 草药和营养保健品.

背景情况:

深度环氧化溶剂 (DES) 为传统溶剂提供了可持续的替代品.
草本提取物富含具有抗氧化特性的生物活性化合物.
超声波辅助提取 (UAE) 是一种有效的化合物隔离方法.

研究的目的:

评估基于胆化物 (ChCl) 的DES用于从草药中超声波辅助提取 (UAE) 抗氧化剂.
为了比较ChCl:马龙酸 (MalA),ChCl:甘油 (Gly) 和ChCl:葡萄糖 (Glu) 与常规溶剂的效率.
分析提取物中的酸,黄和元素组成.

主要方法:

阿联的抗氧化剂来自香,,刺和薄荷,使用三个DES和50%的甲醇/乙醇.
通过ABTS,DPPH和CUPRAC测定进行抗氧化能力评估.
使用超高性能液态染色学 (UPLC) 对化合物的定量分析.
使用感应合等离子体质谱法 (ICP-MS) 进行元素分析.

主要成果:

胆化物:马龙酸 (1:1) DES产生了最高的抗氧化潜力和化合物含量.
与50%的甲醇和乙醇相比,绿色溶剂提取的抗氧化剂总量明显较低.
元素分析揭示了宏观和微量营养素的特征,包括有毒的.

结论:

胆化物:马龙酸是一种有前途的DES,用于从草药中提取生物活性化合物.
在这项研究中,传统溶剂在总抗氧化剂提取方面表现优于绿色DES.
了解元素和抗氧化剂成分对于草药的工业应用至关重要.

关键词:

抗氧化能力的抗氧化能力.抗氧化剂化合物抗氧化剂化合物环保的溶剂环保的溶剂草药草药草药是一种感应合等离子体质谱学多元素形状的多元素形状超高性能液体色谱学超高性能液体色谱学超声波辅助的提取方法

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