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Solid-phase Synthesis of [4.4] Spirocyclic Oximes
Published on: February 6, 2019
一个由亚酸替代的8个成员环梯的合成西洛和其在催化中的应用
Yujia Liu1, Niyaz Yagafarov1, Koki Shimamura1,2
1Department of Chemistry and Chemical Biology, Graduate School of Science and Technology, Gunma University, 1-5-1 Tenjin-cho, Kiryu 376-8515, Japan.
研究人员合成了一种新的亚酸功能化的梯子,这是混合材料的多功能构建块. 这种化合物被用来创建用于铜催化酒精脱的多牙联体,显示了催化潜力.
科学领域:
- 有机化学 有机化学
- 材料科学是一种材料科学.
- 催化剂是一种催化剂.
背景情况:
- 梯子石是独特的氧结构,在材料科学中具有潜在的应用.
- 这些结构的功能化是开发新型混合材料和催化剂的关键.
研究的目的:
- 为了合成一种新型合成类型的三环8-8-8梯子,西洛与亚齐多组功能化.
- 为了探索这种功能化的梯子的实用性,西洛作为混合材料和连接物的构建块.
- 为了评估在酒精氧化脱过程中衍生联体的催化活性.
主要方法:
- 通过可扩展的方法合成一个四乙烯替代的8-8-8梯子.
- 通过水化和核替代与亚基组的功能化.
- 通过与2-乙烯基二烯的化学反应,形成一个多联体.
- 铜催化酒精氧化脱反应使用合成的联结体.
主要成果:
- 成功合成了第一个合成类型的三环8-8-8梯子西洛与四个亚齐多群的优异产量.
- 亚酸功能化的梯子化合物作为一个多功能构建块的表征.
- 通过点击化学制备一个含有四个2-triazole-pyridyl部分的多牙联体.
- 在铜催化酒精氧化脱过程中证明了联体的潜力.
结论:
- 这种新型的azido-functionalized laddersiloxane是先进材料的宝贵前体.
- 衍生出的多联体对催化应用有前途,特别是用于酒精脱.
- 这项工作扩大了用于化学合成和催化作用的功能化梯形氧化物的范围.
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