检查皮肤疾病和自闭症谱系障碍 (ASD) 之间的流行,特征和潜在联系
Laila Yousif Al-Ayadhi1,2, Nadra Elyass Elamin2, Abdulaziz Madani3
1Department of Physiology, College of Medicine, King Saud University, Riyadh 11451, Saudi Arabia.
Journal of clinical medicine
|January 25, 2025
概括
像湿疹这样的皮肤疾病与自闭症谱系障碍 (ASD) 有着显著的联系. 这项研究在ASD患者中发现过敏和亚托皮性疾病的发病率更高,这表明需要进一步研究的潜在联系.
科学领域:
- 皮肤病学和精神病学
- 神经发育障碍 研究 研究 神经发育障碍
- 公共卫生和流行病学
背景情况:
- 越来越多的证据表明,皮肤疾病与自闭症谱系障碍 (ASD) 风险增加之间存在相关性.
- 皮肤状况可能会对ASD患者的生活质量产生负面影响,影响社会互动,行为和认知功能.
- 喘,焦虑和自身免疫性疾病等并发症经常在ASD人群中与皮肤问题一起观察到.
研究的目的:
- 与对照组相比,研究自闭症谱系障碍 (ASD) 患者皮肤病症状的患病率.
- 为了确定与ASD相关的特定皮肤疾病和过敏.
- 探索ASD患者皮肤疾病,过敏和其他并发症之间的关系.
主要方法:
- 一项使用在线问卷的观察性,横截面研究.
- 数据收集发生在2022年8月至2023年1月之间.
- 统计分析涉及描述性和非参数性测试,以比较ASD个体和对照组之间的皮肤学发现.
主要成果:
- 该研究包括363名参与者,其中189人 (52.1%) 被诊断为ASD,174人 (47.9%) 作为对照.
- 患有自闭症的个体患喘,焦虑,抑郁和自身免疫性疾病的比率显著更高 (p < 0.001).
- 皮肤过敏 (50%),食物过敏 (22.2%) 和呼吸道过敏 (14.8%) 在ASD组中明显更为普遍. 湿疹,皮肤干燥和也与ASD有很强的关联 (p < 0.0001).
结论:
- 无形性疾病,包括湿疹,喘和各种过敏,与自闭症谱系障碍 (ASD) 有着显著的关联.
- 这些发现突出了皮肤病和自闭症之间的潜在联系,需要进一步调查.
- 建议进行较大的基于人群的研究,以准确确定皮肤疾病,并发症和ASD之间的患病率和关系.
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