对COVID-19和非COVID-19气管切除患者的比较:并发症,生存和死亡风险因素
Marta Mesalles-Ruiz1,2, Maitane Alonso1,2, Marc Cruellas1,2
1Otorhinolaryngology Department, Hospital Universitari de Bellvitge, Carrer de la Feixa Llarga, s/n, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
需要气管切除术的COVID-19患者的死亡率高于非COVID-19患者. 女性性别和心脏病等因素增加了这些COVID-19患者的死亡风险.
科学领域:
- 关键护理医学 关键护理医学
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 气管切除术是重症监护中常见的一种手术.
- 严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 感染对气管切除患者的影响需要进一步调查.
- 了解结果和风险因素对于管理这些复杂的案件至关重要.
研究的目的:
- 为了比较COVID-19和没有COVID-19的气管切除患者的结果.
- 为了确定与COVID-19气管切除患者的严重程度和死亡率增加相关的因素.
主要方法:
- 追溯的,单中心的队列研究.
- 将COVID-19气管切除术患者 (2020年5月至2022年2月) 与非COVID-19气管切除术队列进行比较.
- 对死亡风险因素的分析,包括患者人口统计,并发病症和心肺切除术前呼吸机参数.
主要成果:
- 与非COVID-19患者 (27.3%) 相比,COVID-19气管切除患者的死亡率明显更高 (50%).
- 在COVID-19患者中,独立的死亡风险因素包括女性性别,缺血性心脏病,高心筋切开前PEEP和INR,以及呼吸道并发症.
- 根据SARS-CoV-2感染状况或气管切除技术,并没有观察到并发症率的显著差异.
结论:
- 气管切除术技术,包括床边皮穿式气管切除术,没有影响并发症率,出院状态或死亡率.
- COVID-19感染与气管切除术患者的死亡率增加有关.
- 确定特定的风险因素对于改善患者管理和结果至关重要.
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