一种非侵入性微循环监测的新方法:使用氧度脉冲波量化毛细血管补充时间
Yuxiang Xia1, Xinrui Wang1, Zhe Guo2
1School of Clinical Medicine, Tsinghua University, 30 Shuangqing Road, Haidian District Beijing, Beijing 102218, China.
Sensors (Basel, Switzerland)
|January 25, 2025
概括
开发了一种新的毛细血管补充时间 (CRT) 测量系统,显示可靠和可重复的结果. 这种非侵入性设备提供快速的微循环监测,实现高医生和患者的满意度.
科学领域:
- 生物医学工程 生物医学工程
- 医疗器械 医疗器械
- 微循环研究 微循环研究
背景情况:
- 毛细血管补充时间 (CRT) 是外周循环的临床指标.
- 现有的CRT测量方法可能是主观的,耗时的.
- 需要一个可靠和客观的系统来测量CRT.
研究的目的:
- 开发和评估一种用于测量毛细血管补充时间的新系统.
- 评估开发的CRT测量系统的可靠性和可重复性.
- 调查新设备的临床可行性和用户满意度.
主要方法:
- 利用电磁压力技术,自动压缩和释放手指.
- 采用压力传感和光电体积脉冲波分析用于动态血流监测.
- 对71名受试者进行了研究,以评估测量时间,所需的测量,一致性 (A组) 和可重复性 (B组).
- 通过问卷收集医生和患者满意度数据.
主要成果:
- 成功开发了一种毛细血管补充时间计,每次测量平均测量时间为18秒.
- 实现了高满意度:医生98.3%,患者100%.
- 在A组中表现出极好的一致性,A组的类内相关系数为0.995,B组的可重复性显著 (p > 0.05).
结论:
- 开发的系统提供了快速有效的微循环的非侵入性监测.
- 毛细管补充时间计测试机产生一致和可重复的CRT测量结果.
- 该设备支持微循环评估的机械化和标准化.
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