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由乳酸细菌发酵的玉米蛋白水解剂的抗疲劳活性

Nan Hu¹, Jingyi Sun¹, Yujia Cao¹

¹Heilongjiang Provincial Key Laboratory of Corn Deep Processing Theory and Technology, College of Food and Bioengineering, Qiqihar University, Qiqihar 161006, China.

|January 25, 2025

概括

乳酸细菌发酵的玉米蛋白水解盐 (FCH) 显著提高了小鼠的运动耐力. FCH改善了与疲劳相关的生理标志物,并积极调节肠道微生物群,特别是增加了乳杆菌的丰度.

科学领域:

营养和新陈代谢营养和新陈代谢
微生物学微生物学
运动生理学运动生理学

背景情况:

疲劳显著影响身体表现和生活质量.
确定有效的干预措施来对抗疲劳至关重要.
肠道微生物群在调节疲劳中的作用是一个新兴的研究领域.

研究的目的:

在小鼠模型中研究乳酸细菌发酵的玉米蛋白水解盐 (FCH) 的抗疲劳作用.
探索FCH,疲劳指标和肠道微生物菌群之间的关系.

主要方法:

用运动耐力测试在小鼠身上建立了疲劳模型.
在血清,肝脏和骨肌肉中评估了疲劳的生理和生化标志物.
分析了肠道微生物多样性,以了解FCH-肠道菌群与疲劳的联系.

主要成果:

高剂量的FCH显著延长了承重游泳时间 (1.96x) 和跑步时间 (2.63x).
FCH降低了血液中的乳酸 (16.00%) 并使乳酸脱酶和尿素水平正常化.
FCH增加了抗氧化能力 (SOD1.84倍,谷甲1.72倍) 并恢复了糖原储量 (肌肉1.81倍,肝脏5.81倍).
FCH治疗增加了肠道微生物群中的 * Lactobacillus * 的相对丰度,这与肌肉糖原和 SOD 水平有积极的相关性.

结论:

在小鼠中,FCH表现出显著的抗疲劳特性.
通过改善关键生理和生化指标,FCH可以缓解疲劳.
调节肠道微生物群,特别是乳酸菌,是FCH抗疲劳作用的关键机制.

关键词:

这是一种抗疲劳的药物.玉米蛋白质的水解剂是玉米蛋白质的水解剂.发酵发酵发酵发酵我们的肠道微生物群.乳酸细菌是一种乳酸细菌.

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