对重症儿童间歇性和持续性肠道食的评估
Merve Misirlioglu1, Dincer Yildizdas2, Faruk Ekinci2
1Department of Pediatric Intensive Care, Faculty of Medicine, Mersin University, Mersin 33079, Türkiye.
Nutrients
|January 25, 2025
概括
与连续肠道养 (CEF) 相比,重症儿童的间歇肠道养 (IEF) 显示出较少的代谢问题和食不耐受性. 在第7天,IEF还导致了更好的卡路里和蛋白质摄入量.
科学领域:
- 儿科重症监护医药 儿科重症监护医药
- 临床营养学 临床营养学
- 胃肠病学 胃肠病学
背景情况:
- 危急病患者的营养不良会增加由于营养不足而导致的发病率和死亡率.
- 肠道营养对于管理儿科重症监护中的营养缺陷至关重要.
研究的目的:
- 为了比较间歇性肠道养 (IEF) 与重症儿科患者的连续肠道养 (CEF) 的疗效和安全性.
- 为了确定一个肠道养方法是否在改善营养状况和减少并发症方面优越.
主要方法:
- 一项多中心前性研究,涉及510名患病危急的儿科患者,接受管内肠道营养.
- 在3个月的随访期内评估人体测量数据,卡路里和蛋白质摄入量以及食不耐受症的迹象.
- 在接受IEF和CEF的患者之间对结果的比较.
主要成果:
- 与间歇性肠道养 (IEF) 组相比,持续肠道养 (CEF) 组的代谢异常率 (20.2%) 和肠道营养不耐受率 (49.5%) 显着更高.
- 在IEF和CEF之间,在第2天和第7天实现目标卡路里摄入量没有显著差异.
- 在第7天,IEF组的卡路里和蛋白质摄入量明显高于CEF组.
结论:
- 间歇性肠道养 (IEF) 与重症儿科患者的肠道营养不耐受和代谢异常率较低有关.
- 与CEF相比,IEF在第7天显示出更高的卡路里和蛋白质摄入量.
- 建议进行进一步的随机对照试验以验证这些发现.
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