探索饮食和体育活动对代谢参数的影响中的性别差异
Stefania Gorini1,2, Elisabetta Camajani1,2, Alessandra Feraco1,2
1Department for the Promotion of Human Science and Quality of Life, San Raffaele Open University, Via di Val Cannuta, 247, 00166 Rome, Italy.
Nutrients
|January 25, 2025
概括
像地中海饮食和体育活动这样的生活方式干预措施显示出性别特异的代谢益处. 根据个体生理学和活动类型量身定制策略,优化了超重成年人的结果.
科学领域:
- 代谢健康 代谢健康
- 预防心血管疾病 预防心血管疾病
- 肥胖管理 肥胖管理
背景情况:
- 对生活方式干预的代谢反应的性别差异尚未得到充分理解.
- 超重的成年人经常在管理代谢健康方面面临挑战.
- 生活方式干预对于改善超重人口的健康结果至关重要.
研究的目的:
- 评估六个月的地中海饮食 (MD) 和体力活动干预对超重成人代谢参数的影响.
- 调查对干预的代谢反应的性别特异性差异.
- 探索不同类型的体育活动如何影响代谢结果.
主要方法:
- 在肥胖诊所 (意大利罗马) 进行前性队列研究.
- 205名超重的成年人 (107名男性,98名女性) 积极改变生活方式.
- 参与者自行选择了有氧,无氧,联合或无活动组;评估了脂质配置文件,肝脏标志物和禁食葡萄糖.
主要成果:
- 男性的总胆固醇 (TC) 和LDL以及肝脏酶氨酸转移酶 (ALT) 的降低更大.
- 妇女的HDL胆固醇显著增加.
- 禁食葡萄糖在两性都下降了;无氧活动有利于男性的脂质代谢,而有氧活动有利于女性的HDL和肝脏标志物.
结论:
- 联合地中海饮食和体力活动干预措施的代谢益处因性别和活动类型而异.
- 考虑性别特异性生理学和运动方式的个性化治疗策略是必不可少的.
- 优化干预措施可以改善超重个体的心血管风险因素管理.
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