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Updated: May 30, 2025

Solubility of Hydrophobic Compounds in Aqueous Solution Using Combinations of Self-assembling Peptide and Amino Acid
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配方研究 一种聚氨基甲酸) 膜形成溶液用于通过皮肤给药

Chiara G M Gennari1, Antonella Casiraghi1, Francesca Selmin1

  • 1Department of Pharmaceutical Sciences, Università degli Studi di Milano, via G: Colombo, 71, 20133 Milano, Italy.

Pharmaceutics
|January 25, 2025
PubMed
概括

这项研究开发了一种使用Eudragit® EPO (EuE) 聚合物的新型薄膜形成系统 (FFS). 最佳配方增强了药物的皮肤透性和保留力,突出了增塑剂的关键作用.

关键词:
欧德拉吉特® E E药物输送系统是药物输送系统.形成膜的溶液形成膜的溶液塑化剂 塑化剂 塑化剂皮肤的透性.过度和是一种超和.通过皮肤传递药物.三胺氨酸的三胺氨酸.

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Factors Affecting Dissolution: Polymorphism, Amorphism and Pseudopolymorphism01:21

Factors Affecting Dissolution: Polymorphism, Amorphism and Pseudopolymorphism

Polymorphism refers to the existence of a drug substance in multiple crystalline forms, known as polymorphs. Recently, this term has been expanded to include solvates (forms containing a solvent), amorphous forms (non-crystalline forms), and desolvated solvates (forms from which the solvent has been removed).
Some polymorphic crystals possess lower aqueous solubility than their amorphous counterparts, leading to incomplete absorption. For instance, the oral suspension of Chloramphenicol, which...
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