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Updated: May 30, 2025

Development of Compendium for Esophageal Squamous Cell Carcinoma
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Development of Compendium for Esophageal Squamous Cell Carcinoma

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苏莫特异性酶5通过NF-κB-SLC1A3轴促进食道状细胞癌的生长

Chaoxiang Du1,2, Yunfan Hu1, Xinyu Yang1

  • 1Department of Thoracic Surgery, Zhongshan Hospital, Fudan University, 200032 Shanghai, China.

Frontiers in bioscience (Landmark edition)
|January 25, 2025
PubMed
概括

小型泛素类修饰剂 (SUMO) 特定的化酶5 (SENP5) 在食道状细胞癌 (ESCC) 中被上调. 抑制SENP5通过影响NF-κB-SLC1A3轴来减缓ESCC的发展,这表明SENP5是治疗点.

关键词:
在 NF-κBB 中.这就是SENP5P的意义.消化管皮细胞癌的癌症.

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