压力的沉默流行:对月经周期和排卵的影响
Mariam Saadedine1, Sarah L Berga2, Stephanie S Faubion3,4
1Department of Obstetrics and Gynecology, George Washington University, Washington, District of Columbia, USA.
Stress (Amsterdam, Netherlands)
|January 25, 2025
概括
现代压力影响年轻一代,扰乱月经周期,并可能导致功能性下丘脑缺血症 (FHA). 这种情况带来了严重的健康风险,突出了需要更多的研究和综合治疗的需要.
科学领域:
- 神经内分泌学神经内分泌学
- 生殖健康 生殖健康
- 精神病体医学是一种精神病体医学.
背景情况:
- 压力是一种全球性流行病,由于技术进步和社会压力,尤其影响年轻人.
- 慢性压力会破坏下丘脑-垂体-上腺 (HPA) 轴,影响包括月经周期在内的生理过程.
- 功能性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性性
研究的目的:
- 突出神经内分泌机制,通过压力影响月经周期.
- 将功能性下丘脑缺血 (FHA) 定义为压力诱导的生殖功能障碍的严重表现.
- 要强调与FHA相关的重大健康后果和研究差距.
主要方法:
- 关于压力,神经内分泌学和生殖健康的最新文献的综述.
- 慢性下丘脑-垂体-上腺 (HPA) 轴激活对性腺激素释放激素 (GnRH) 脉动性的影响分析.
- 检查功能性催眠性催眠症的频谱及其最严重的形式,FHA.
主要成果:
- 压力可变地扰乱了GnRH驱动,导致一系列的月经不规则,包括FHA.
- FHA是一种复杂的神经内分泌病症,与阿美诺雷亚,不孕不育,骨损失,内皮功能障碍和心血管风险有关.
- 尽管它的流行和严重后果,FHA的研究仍然有限.
结论:
- 联邦住房管理局 (FHA) 代表着严重的健康负担,需要临床意识和全面的管理策略.
- 解决行为和生物心理社会压力因素对于管理慢性HPA轴激活至关重要.
- 进一步的大规模,长期研究对于确定FHA流行,健康影响和治疗疗效至关重要.
更多相关视频
07:26Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm
Published on: May 4, 2020
3.3K
07:59Using Practice Testing, Public Speaking, and Source Monitoring to Examine the Influences of Learning Strategies and Stress on Episodic Memory
Published on: June 14, 2019
7.9K
相关概念视频
01:22Hormonal Regulation of the Menstrual Cycle
277
The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
277
01:30Hormonal Control of the Ovarian Cycle
393
The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
393
01:27Ovarian Cycle
954
The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle...
954
01:19The Menstrual Cycle
675
The menstrual cycle is a recurrent sequence of changes in the uterine endometrium, specifically its functional layer, the stratum functionalis. This cycle prepares the uterus for potential pregnancy. This cycle typically spans 21–35 days, averaging 28 days, and aligns with the ovarian cycle, regulated by fluctuating levels of ovarian hormones, primarily estrogen and progesterone.
The menstrual phase occurs from days 1 to 5 and involves the shedding of the stratum functionalis, as a...
The menstrual phase occurs from days 1 to 5 and involves the shedding of the stratum functionalis, as a...
675
01:19Secretory Phase
494
The secretory phase of the menstrual cycle, spanning from day 14 to 28 in a typical 28-day cycle, is a period of significant physiological changes in the female reproductive system. This phase commences immediately after ovulation and is characterized by the preparation of the endometrium for potential embryo implantation.
Following ovulation, the corpus luteum, a temporary endocrine structure, produces progesterone and estrogens. These hormones stimulate the growth and coiling of endometrial...
Following ovulation, the corpus luteum, a temporary endocrine structure, produces progesterone and estrogens. These hormones stimulate the growth and coiling of endometrial...
494
01:20Psychological Responses to Stress
41
Psychological responses to stress encompass the various cognitive and emotional reactions individuals experience when faced with challenging or threatening situations, such as a job loss. Prolonged exposure to stressors can disturb emotional balance, increasing negative emotions (e.g., anxiety and sadness) and diminishing positive emotions (e.g., joy and satisfaction). These persistent emotional shifts are associated with an increased risk of both physical illness and mental health issues, such...
41