基于计算机断层扫描的诺莫图谱用于估计经过部分囊切除术的膀癌患者的无进展生存概率
Ting Cao1,2, Xiaolin Zhu2, Chuanchao Guo2
1The First Central Clinical College, Tianjin Medical University, Tianjin, China.
Abdominal radiology (New York)
|January 25, 2025
概括
一种新的诺莫格拉姆模型预测了部分囊切除术 (PC) 后膀癌 (BCa) 患者的无进展生存期 (PFS). 这个工具有助于治疗决策和BCa患者的后续安排.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
背景情况:
- 膀癌 (BCa) 是一个重大挑战,需要准确的预后工具.
- 部分囊切除术 (PC) 是一种治疗选择,但预测结果仍然至关重要.
研究的目的:
- 开发一种预后模型,用于估计BCa患者接受PC的无进展生存 (PFS) 概率.
- 确定关键的临床和计算机断层扫描 (CT) 预测PFS的特征.
主要方法:
- 分析了接受PC的106名BCa患者的队列.
- 评估了临床数据和CT成像特征.
- 用单变Cox,LASSO和多变Cox回归分析来构建一个名ogram.
主要成果:
- 最终的名图包括性别,组织学,曲的血管和周围脂肪浅.
- 该模型实现了Harrell的一致性指数 (C指数) 0.752.
- 1,2,3年ROC曲线下的面积 (AUC) 分别为0.733,0.789和0.833,表明了良好的预测准确性.
结论:
- 结合临床因素的CT-based nomogram可以在PC后预测BCa患者的PFS.
- 该模型提供了一种可行的方法,以协助治疗选择和后续计划.
- 诺米图表显示了强大的校准和预测性能,直至手术后3年.
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